What must Legend Drugs carry according to the Durham-Humphrey Amendment?

Legend drugs must carry the statement "Caution: Federal law prohibits dispensing without a prescription" as mandated by the Durham-Humphrey Amendment. This amendment established a clear distinction between prescription medications and over-the-counter (OTC) medications, emphasizing the importance of medical supervision when using these drugs. The requirement for this specific labeling serves as a reminder that certain medications require a licensed healthcare professional's oversight to ensure safe and appropriate use, thus protecting patient safety.

Additionally, this labeling helps to reinforce the legal aspect surrounding the dispensing of prescription medications, indicating that they cannot be sold or distributed without a valid prescription from a qualified healthcare provider. This is crucial in managing prescription use and preventing misuse or mishandling of potentially risky medications. The focus on the federal requirement underscores the regulatory framework that governs prescription drugs to promote health and safety within the healthcare system.